Lock My PC 3.4
Ensure that no one but you can access your private data when you leave your computer unattended with Lock My PC.
Just press the hotkey on your keyboard or double-click the TaskTray icon to lock down your PC. Once that is done, only people who know the correct password may access the computer. What others will see is your lock screen. Windows hotkeys and mouse movement are disabled. The program is fully customizable: from custom lock screen image to security level settings every possible option can be configured to suit your needs. It also includes password expiration and administrative controls.