Tofu is a novel application to address the common problem that people don't like reading text on the screen.
In Tofu, text is arranged in columns, and each column is only as high as your window. So lines are nice and narrow, and they don't move about vertically. You just scroll from column to column horizontally, and feel more in control. Bonus: your text is now also in easy-to-digest chunks.
Tofu also includes some other useful features to make reading easier. To search for a word, simply start typing it; Tofu will find to the next matching instance as you type. There's a system-wide Service, so you can quickly move some text from a web page into Tofu. And it lets you navigate using your voice, so you can literally sit back and read.
Mac OS X 10.4 or higher.