Extensible System Monitor, ESM is a daemon that lets you tie together plug-ins in order to monitor your system.
You could use the included esmsyslog plug-in, which would notify you by e-mail of any "emerg" syslog messages, such as a harddrive failure.
If you then decide that you also want to know if TripWire detects anything, you can use another monitor that reports on TripWire.
If you want to know if the load on your system suddenly goes up, you can do that, too.
ESM will get the results of all of these monitors, make a system report and then send that report with a sender. All of this is done automatically, so you can get some sleep.